A team of researchers found the involvement of extracellular-signal-regulated kinase (ERK), which is a brain protein that initiates the neuropsychiatric effects of THC.
According to the study, rats with THC had larger levels of activated ERK, more anxiety-related behaviours, and more susceptibility to learning based on fear. Rats with both CBD & THC behaved similarly to control rats: they exhibited low levels of anxiety- including behaviours, had regular levels of activated ERK, and were less susceptible to fear-based learning.
Based on these findings, the researchers hypothesise that CBD forbids THC's harmful side effects by preventing it from overstimulating the ERK route in the hippocampus.
Read more about the research - https://scitechdaily.com/molecular-cannabis-study-reveals-how-cbd-offsets-the-psychiatric-side-effects-of-thc/